Volume 7, Issue 1 (4-2016)                   JAP 2016, 7(1): 1-12 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mohammadtaheri F, Tavakol K, Gheysari R, Akhlaghdoost M. the effectiveness of oral peppermint extract on migraine. JAP 2016; 7 (1) :1-12
URL: http://jap.iums.ac.ir/article-1-5257-en.html
1- , farmoh.taheri@yahoo.com
Abstract:   (19212 Views)

Introduction: Different type of drugs are used in the pharmacologic prophylaxis of migraine. Each of them has their own efficacy and side effects. In addition to pharmacological drugs, some studies have also suggested the use of the alternate and herbal remedy in migrane.Peppermint have a long history of use in some disorders, including headache. In this study we evaluate the effectiveness of  oral peppermint extract (menthol) in migraine.

Methods and materials: This study is a randomized clinical trial in centers: Sadaf pain clinic, Pars Hospital and Amir almomenin Hospital in Tehran. In this study 40 patients, aged between 18 to 65 years, (2 to 8 attacks per month and being  on prophylactic  treatment), observed for one month then  oral menthol 2%  added for 1 month to their treatment(5 drops after lunch and dinner). Patients were followed for frequency of attacks, headache severity, duration of attacks and associated symptoms of attacks, one month before and one month after consumption of the peppermint extracts.

Results: Peppermint caused a significant decrease in frequency, severity and duration of  attacks  (P-value <0.05). Of symptoms: Photophobia & Phonophobia improved significantly (P-value <0.05), whereas no significant changes was observed in  nausea and vomiting  (P-value >0.05). 

Conclusion: Our study  showed that peppermint extract (menthol) can reduce significantly intensity, duration and frequency of migraine attacks in combination to prophylactic pharmacologic therapy.

Keyword: Effectiveness, peppermint, migraine

Full-Text [PDF 378 kb]   (5434 Downloads)    
Type of Study: Original | Subject: Chronic pain managment
Received: 2015.12.10 | Accepted: 2016.12.9 | Published: 2016.12.30

Add your comments about this article : Your username or Email:

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Anesthesiology and Pain

Designed & Developed by : Yektaweb