Journal of Anesthesiology and Pain

Introduction: Renal colic is a complex of symptoms wich is indicated of obstruction in urinary tract. Pain result from stone passage is one of the most sever and intractable pains. For pain control different agents has been used such as opium's, NSAIDs, calcium channel blockers, parental acetaminophen , … . Method: After considering inclusion and exclusion criteria, 300 patients with renal colic entered the study. Questioner filled for each patient by demographic and study variables. patients divided into two groups randomly and treated with intravenous ketorolac or intravenous morphine. Pain score was documented by VAS chart before, 20, 40 and 60 minutes after injection. Then decrease in pain score and rescue therapy requirement in both group compared. Results: There was no difference between age and sex between two groups. More over there was no significant difference in mean size of the stone in two groups. Mean pain free time in morphine group was 27.7± 10.1 minute and in ketorolac group was 17.4 ± 10.2 minute ( p< 0.001). Rescue therapy was significantly more in morphine group (p=0.001). Also pain score decrease in 20, 40 and 60 minutes was significantly higher in ketorolac group. (p < 0.01) Conclusion: Totally parental ketorolac had more effectiveness and speed of action than parental morphine. Although ketorolac was no significant complications.