Journal of Anesthesiology and Pain

Aim and Background:

Hypotension and nausea are common side effects during spinal

anesthesia. This study compared the incidence of hypotension and nausea-vomiting induced by

bupivacaine and lidocaine in parturients undergoing caesarean section under spinal anaesthesia.

Methods and Materials:

In this clinical trial, 120 parturients undergoing caesarean section were

randomly allocated into two groups. 60 patients received subarachnoid lidocaine 5% (75-100 mg)

and the other group of patients received bupivacaine 0.5% (12-15 mg). If systolic blood pressure

decreased to 80 mm Hg or less than 70% of the pre-anesthesia value, 5mg ephedrine was

injected. We evaluated Blood pressure each 3 minutes up to 15 min and every 5 min thereafter till

the end of the recovery stay.

Findings:

There was no statistically significant difference in the incidence of nausea -vomiting

between the two groups after spinal anesthesia. On the other hand, there was significant

difference in systolic blood pressure 12 minutes after the procedure and also a significant

difference was noted in diastolic blood pressure 3, 9, 15, and 40 minutes after performing spinal

anesthesia (P < 0.05). The amount of ephedrine used in both groups did not show either any

significant difference.

Conclusions:

Intrathecal bupivacaine may yield more hemodynamic stability than intrathecal