Volume 2, Issue 7 (21 2012)                   JAP 2012, 2(7): 81-0 | Back to browse issues page

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Behrouz Zaman, Alirezqa Siamdoust, Reza Tarjoman M A F I M A. Comparison of sedative effect of remifentanil with propofol in senile cataract surgery under retrobulbar block. JAP. 2012; 2 (7) :81-0
URL: http://jap.iums.ac.ir/article-1-43-en.html
Abstract:   (3256 Views)


Because general anesthesia is not a good choice in elderly ASA>II patients candidate for cataract surgery performored by ophthalmology Residents and lack of cooperation in these patients, sedative effect and hemodynamic status and side effects of two drugs, Remifentanil & propofol  are compared.


Methods :

In a Randomized clinical trial on 60 patients candidate for cataract surgery which were divided in two group each containing 30 patients were compared. In group A (remifentanil group), patients were sedated with a bolus dose of 0.5 µg/kg within 1 minute , and maintenance dose of 0.05 µg/kg/min. In group B ( propofol  group) ,  patients were sedated with a bolus dose of 0.25 µg/kg, and maintenance dose of 25 µg/kg/min. After retrobulbar block was performored for all the patients by residents. Hemodynamic responses, including  HR , DBP , SBP  and O2Sat and sedation level according to MOAA/SS  were measured .

Modified Observers Assessment of Awareness/Sedation Scale   =   MOAA/SS           



 Sedation was deeper in  group A  (Remifentanil ) measured in all times after Block and were statistically meaningful (p<0.05) .The heart rate was  reduced in  group A after 20 minutes after Block and were statistically meaningful ( p<0.05). 7 Cases  in group A ( Remifentanil ) had  nausea after drug administration  (P=0.011).


 Remifentanil can induce high level of sedation for patients compare to propofol. But Nausea could be troublesome and in this point propofol has less adverse effect.


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Type of Study: Original | Subject: General

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