دوره 2، شماره 7 - ( 3-1391 )                   جلد 2 شماره 7 صفحات 81-0 | برگشت به فهرست نسخه ها


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Behrouz Zaman, Alirezqa Siamdoust, Reza Tarjoman M A F I M A. Comparison of sedative effect of remifentanil with propofol in senile cataract surgery under retrobulbar block. JAP. 2012; 2 (7) :81-0
URL: http://jap.iums.ac.ir/article-1-43-fa.html
علیمیان مهزاد، ایمانی فرناد، آل بویه محمودرضا، زمان بهروز، صیام دوست علیرضا، پرشکوه رضا. مقایسه اثرات سداتیو رمیفنتانیل با پروپوفول در اعمال جراحی کاتاراکت سالمندان تحت بلوک موضعی رترو بولبار. بیهوشی و درد. 1391; 2 (7) :81-0

URL: http://jap.iums.ac.ir/article-1-43-fa.html


چکیده:   (2906 مشاهده)

Background:

Because general anesthesia is not a good choice in elderly ASA>II patients candidate for cataract surgery performored by ophthalmology Residents and lack of cooperation in these patients, sedative effect and hemodynamic status and side effects of two drugs, Remifentanil & propofol  are compared.

 

Methods :

In a Randomized clinical trial on 60 patients candidate for cataract surgery which were divided in two group each containing 30 patients were compared. In group A (remifentanil group), patients were sedated with a bolus dose of 0.5 µg/kg within 1 minute , and maintenance dose of 0.05 µg/kg/min. In group B ( propofol  group) ,  patients were sedated with a bolus dose of 0.25 µg/kg, and maintenance dose of 25 µg/kg/min. After retrobulbar block was performored for all the patients by residents. Hemodynamic responses, including  HR , DBP , SBP  and O2Sat and sedation level according to MOAA/SS  were measured .

Modified Observers Assessment of Awareness/Sedation Scale   =   MOAA/SS           

 

Results:

 Sedation was deeper in  group A  (Remifentanil ) measured in all times after Block and were statistically meaningful (p<0.05) .The heart rate was  reduced in  group A after 20 minutes after Block and were statistically meaningful ( p<0.05). 7 Cases  in group A ( Remifentanil ) had  nausea after drug administration  (P=0.011).

Conclusion:

 Remifentanil can induce high level of sedation for patients compare to propofol. But Nausea could be troublesome and in this point propofol has less adverse effect.

 

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