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Showing 2 results for Electroconvulsive Therapy
Effective factors in peripheral seizure production in patients undergoing Electroconvulsive Therapy from anesthesia perspective
Mohammad Haghighi, Tahereh Chavoshi, Samaneh Ghazanfar Tehran, Gita Khanjanian, Robabeh Soleimani, Mona Nematllahy, Samira Mirzababae, Batool Montazeri,
Volume 6, Issue 2 (7-2015)
Abstract
Aim and Background: Electroconvulsive therapy(ECT) is one of the most effective and prompt therapies for
severe psychotic issues. This study aims to distinguish the impact of age, disease and medications on the seizure
caused by ECT.
Methods and Materials: 123 patients were studied and categorized according to their age, psychotic disorder
and medications (anti-psychotics, anti-depressive or both of them). The correlation of these variants with seizure
duration were discussed in every session of ECT.The seizure duration was recorded based on clinical convulsion
and EEG parameters. The failure or success of ECT was evaluated by seizure time measurement to be less or
greater than 20 sec, respectively.
Findings: There was no significant difference observed between men and women in regards to the average
seizure duration in different sessions (6 sessions) (P=0.25).There was either no significant difference observed
in seizure duration in various sessions between patients under and above 40 years of age(P=0.45). Again
no significant difference was seen in seizure duration among patients with psychotic and mood disorders or
between patients using anti-psychotic or anti- psychotic and anti- depressant drugs for therapy, respectively
(P=0.38 and P=0.14).
Conclusions: Accurate knowledge about patients who are candidate to receive Electroconvulsive Therapy is
very important. Type of psychologic disorder, type of drug protocol and the number of sessions of ECT, all are
the factors which should be considered in every ECT procedure.
Keywords: Electroconvulsive therapy, seizure duration, success rate

Assessment of Propofol and etomidate effect on the duration of convulsion and hemodynamic responses to electroconvulsive therapy
Dr Mehrdad Malekshoar, Dr Hashem Jarineshin, Dr Saeed Kashani, Dr Fereydoon Fekrat, Dr Raziyeh Raz, Dr Majid Vatankhah,
Volume 8, Issue 2 (7-2017)
Abstract

 Aim and Background: Electroconvulsive therapy (ECT) is considered as the most effective treatment method for major depression and psychiatric disorders. Significant hemodynamic changes occur in patients treated with ECT and the duration of seizure after ECT is considered as an important factor in the success of this treatment method. This study aimed to compare the effect of etomidate and propofol on seizure duration and hemodynamic parameters in ECT. Methods and Materials: This study is a double blind clinical trial on 27 patients (54 patient sessions), aged 12-60 years with ASA class I-II. In the first patient session induction of anesthesia for ECT was applied by either propofol (2 mg/kg) or etomidate (0.2 mg/kg) and for the second patient session (with a time interval of 48 hours) the other drug was applied. Systolic blood pressure, diastolic blood pressure and heart rate were measured and recorded in four stages of ECT once before and then 1, 3 and 5 minutes after ECT. Seizure duration was measured in each session. Data analysis was applied by SPSS software and a P value <0.05 was considered significant. Findings: The mean age of participants in this study was 35.9 ± 10.4. The mean duration of seizure during propofol and etomidate anesthesia was 35.14 and 35.74 seconds, respectively (P = 0.240). Mean systolic and diastolic blood pressure and heart rate every time after seizure during propofol anaesthesia was less than etomidate (P =0.05). conclusions: There was no significant difference regarding seizure duration and hemodynamic changes subsequent to ECT, between propofol and etomidate anesthesia
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