Journal of Anesthesiology and Pain

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 Aims and background: This study aimed to compare Rabeprazole with ranitidine on decreasing epigastric pain in patients undergoing vitrectomy surgery in Rasoul-e-Akram hospital during 1391-1392.

 Materials and methods: This study was a double-blinded randomized controlled trial on patients undergoing vitrectomy. Patients were divided into three groups receiving: Rabeprazole (20 mg), Ranitidine (150 mg) and both (20 mg Rabeprazole plus 150 mg ranitidine). After surgery patients were asked about epigastric pain, heartburn, regurgitation, nausea and vomiting. Patients were compared based on these variables.

 Findings: In this study 105 patients with average age of 67.55 years (SD=9.87) were included and divided into three groups, each containing 35 patients. In Rabeprazole group, 8(22.9%), 7(20%), and 4(11.4%) patients had regurgitation at 1, 2 and 4 hours after surgery, respectively. In Ranitidine group this amount was 5(14.3%), 3(8.6%) and 2(5.7%). In the third group this changed to 3(8.6%), 2(5.7%) and 3(8.6%), respectively which was not significantly different among the three groups (P value> 0.05).

 Pain severity after surgery at different hours, was decreased significantly in all groups (P value<0.001) but this was not significantly different among them (P Value= 0.15).

 Conclusion: This study shows that using Ranitidine and Rabeprazole simultaneously or Ranitidine alone decreases pain and regurgitation after elective surgery more than using Rabeprazole alone. Using both of these is effective in decreasing pain after surgery.

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Aim and Background: This study aimed to determine the efficacy of femoral nerve block in adductor canal and comparison it with the classical method of femoral nerve block in terms of pain relief after elective surgery of the knee. Materials and Methods: In this study clinical trial study, 92 patients who were candidate for knee arthroscopy in Rasool Akram hospital during 2014- 2015 were evaluated. All patients were blocked after surgery using femoral nerve block or adductor canal block. 1 g Apotel was infused in each group and in the case of no betterment, additional NSAID was administrated. Severity of pain and sedation was measured. Satisfaction level was also evaluated. Data then were entered to SPSS v. 16and were analyzed. Findings: We found significant difference between two groups from the point of pain in 3, 6 and 24 hour after the block. The highest VAS score was seen in recovery time in both groups, while pain score was 5 in 50% of patients of each group and 5- 6 in 25- 75% of patients. Sedation was statistically different between the two groups just immediately after the block. Satisfaction in femoral group patients was significantly higher than adductor canal group. Adductor canal group significantly received more additional NSAIDS compared to the femoral group. Conclusion: This study showed that patients with femoral nerve block received lower additive analgesic and had more satisfaction, so this method can be used as an effective treatment for elective surgery knee.