Volume 15, Issue 3 (12-2024)
JAP 2024, 15(3): 18-30 |
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Ethics code: IR.IUMS.FMD.REC.1398.444
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Nikoubakht N, Farahmand Rad R, Sehat-Kashani S, Khosravi N, Mohammadi N. Assessment of anesthesia depth in narcotic addicted patients undergoing elective hip fracture surgery. JAP 2024; 15 (3) :18-30
URL: http://jap.iums.ac.ir/article-1-5652-en.html
URL: http://jap.iums.ac.ir/article-1-5652-en.html
Nasim Nikoubakht1 
, Reza Farahmand Rad 2, Saloome Sehat-Kashani1 , Niloofar Khosravi1 , Niloufar Mohammadi1
, Reza Farahmand Rad 2, Saloome Sehat-Kashani1 , Niloofar Khosravi1 , Niloufar Mohammadi1
1- Department of Anesthesiology & Pain, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
2- Department of Anesthesiology & Pain, School of Medicine, Iran University of Medical Sciences, Tehran, Iran ,Dr.rezafarahmandrad@gmail.com
2- Department of Anesthesiology & Pain, School of Medicine, Iran University of Medical Sciences, Tehran, Iran ,
Abstract: (119 Views)
Introduction: There is a growing trend in drug addiction around the world. Addiction is defined as the inability to control the use of a drug, and has a highly variable clinical course. The aim of this study is to investigate both the depth of anesthesia with the help of BIS (Bispectral Index Score) as well as the amount of anesthetic required during anesthesia on narcotics users and healthy individuals aged 18 to 65 years under elective hip fracture surgery.
Methods: In this study, patients undergoing elective hip fracture surgery referred to the operating room of Rasool Akram Hospital in 2019 were evaluated. Patients were examined in one of the two groups: 1.drug addicts and 2.non-addicts. The variables measured include demographic variables, BIS, heart rate, systolic blood pressure, diastolic blood pressure, and the percentage increase in propofol and remifentanil, and recorded in two groups at 0, 15, 30 minutes after the start of the incision.
Results: forty five patients in two groups of addicts (22) and non-addictcs (23) were studied. The Bispectral Index Score( BIS) at minute 0, 15, and 30 after the surgery in the addicted group were more than the non-addicted group; however, the differences were not significant (P>0.05). Heart rate, systolic blood pressure, and diastolic blood pressure at minute 0, 15, and 30 of the surgery were higher among the patients in the addicted group compared to the non-addicted group, but the differences were not significant (P>0.05). The dose of propofol and remifentanil at the first fifteen minutes of surgery was significantly higher in the addicted group patients than among the non-addicted group (P<0.05). However, there was no significant difference between the dose of propofol and Remifentanil at the start of incision, 15 minutes after the start of incision, up until 30 minutes after. The total dose of propofol and Remifentanil in patients in the two groups was not significant difference (P>0.05). There was no significant difference between the frequency of patients in the two groups because of increasing the dose of propofol or Remifentanyl during the first 30 minutes of the start of the incision (P>0.05).
Conclusion: The depth of anesthesia can be controlled with the help of BIS during anesthesia in addicts and the required anesthetic can be reduced by controlling BIS in addicts during anesthesia.
Methods: In this study, patients undergoing elective hip fracture surgery referred to the operating room of Rasool Akram Hospital in 2019 were evaluated. Patients were examined in one of the two groups: 1.drug addicts and 2.non-addicts. The variables measured include demographic variables, BIS, heart rate, systolic blood pressure, diastolic blood pressure, and the percentage increase in propofol and remifentanil, and recorded in two groups at 0, 15, 30 minutes after the start of the incision.
Results: forty five patients in two groups of addicts (22) and non-addictcs (23) were studied. The Bispectral Index Score( BIS) at minute 0, 15, and 30 after the surgery in the addicted group were more than the non-addicted group; however, the differences were not significant (P>0.05). Heart rate, systolic blood pressure, and diastolic blood pressure at minute 0, 15, and 30 of the surgery were higher among the patients in the addicted group compared to the non-addicted group, but the differences were not significant (P>0.05). The dose of propofol and remifentanil at the first fifteen minutes of surgery was significantly higher in the addicted group patients than among the non-addicted group (P<0.05). However, there was no significant difference between the dose of propofol and Remifentanil at the start of incision, 15 minutes after the start of incision, up until 30 minutes after. The total dose of propofol and Remifentanil in patients in the two groups was not significant difference (P>0.05). There was no significant difference between the frequency of patients in the two groups because of increasing the dose of propofol or Remifentanyl during the first 30 minutes of the start of the incision (P>0.05).
Conclusion: The depth of anesthesia can be controlled with the help of BIS during anesthesia in addicts and the required anesthetic can be reduced by controlling BIS in addicts during anesthesia.
Type of Study: Original |
Subject:
General
Received: 2022.05.8 | Accepted: 2024.09.27 | Published: 2024.12.30
Received: 2022.05.8 | Accepted: 2024.09.27 | Published: 2024.12.30
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