Aims and background: Tuberous sclerosis is an autosomal dominant disease characterized by hamartomas lesions in multiple organs. This article reports the case with tuberous sclerosis candidate femur surgery that was performed under general anesthesia without any problem. case report: The patient was a 44 years old man with a weight of 48 kg and height of 162 cm, known case tuberous sclerosis with mental retardation and recurrent seizure under treatment and urology complication lived in disabled sanitarium. After pre operative visite and necessary implementation , patient was underwent general anesthesia with endotracheal intubation and surgery was performed successfully without complications. After surgery the patient was fully conscious and transferred to recovery room with good general appearance and was discharged after three days
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