Journal of Anesthesiology and Pain

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Aim and Background: Many of patients candidate for Transurethral Resection of Prostate (TURP) due to Benign Prostatic Hyperplasia (BPH), also suffer from cardiovascular diseases and are under medication with low dose aspirin (80 mg/daily). Aspirin withdrawal may result in acute cardiovascular syndrome, while its continuation may expose the patient to the risk of post-surgical excessive bleeding. There is not any guideline about whether to discontinue aspirin before TURP or not. This short communication aims to determine the impact of aspirin on intraoperative blood loss. Methods and Materials: A prospective study on 105 TURP candidates was designed, with 26 cases (24.8%) under aspirin medication and 79 cases (75.2%) not. Intra operative bleeding in two groups was compared together. Findings: There is no significant differences in intraoperative blood loss (P>0.05), hemoglobin concentration drop (P>0.05), hematocrit drop (P>0.05), time to urine clearance and blood transfusion between two groups. Blood loss does not have a significant correlation with type of anesthesia. Conclusions: Aspirin does not increase bleeding in TURP. As withdrawal of aspirin can lead to cardiovascular complications routinely aspirin discontinuation in these patients is not recommended.

Keywords: Aspirin; Transurethral Resection of Prostate; Bleeding; Benign Prostatic Hyperplasia

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