Volume 8, Issue 2 (3-2018)                   JAP 2018, 8(2): 61-71 | Back to browse issues page

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dargahi R, ghazi A, hashemi Pazikoueii F, amani F. A comparative study about the efficacy of Entonox Gas analegesia alone and in combination with dexamethasone in painless labor . JAP. 2018; 8 (2) :61-71
URL: http://jap.iums.ac.ir/article-1-5341-en.html
1- Ardabil University of medical sciences
2- Ardabil university of medical sciences , dr.ghaziahmad@gmail.com
Abstract:   (1793 Views)
 Aim and background: Labor pain is often severe. Unrelieved labor pain can have adverse effects on the physiologic status of mother. Pain during labor is accompanied by fear, which is related to slower progress of labor. Accurate measurement and appropriate management of pain is of great concern for medical and nursing personnel. There are choices to be made during pregnancy about options available for pain relief during labor; each    method    has    its    own    risks    and    benefits,    with    variable    efficacy,    availability    and    acceptability.    The    purpose    of this study is the comparison of analgesic effect of inhaling Entonox with and without dexamethasone among women undergoing normal vaginal delivery in Alavi hospital in 1394-95. Materials and Methods: In this clinical trial study in Alavi hospital, 100 women with term pregnancy were observed.    10    people    were    excluded    due    to    various    reasons    and    finally    the    subjects    were    divided    into    two    groups    of A and B, randomly. Group A received inhaled Entonox and placebo (45 cases) and group B received inhaled Entonox and 8 mg intramuscular Dexamethasone (45 cases). VAS and NRS pain score was measured before intervention and 3 hours and 6 hours after intervention. Finally the the Data was analyzed by SPSS. Findings:    Pain    severity    according    to    VAS    and    NRS    score    was    significantly    lower    in    patient    in    group    B    who    received nitrous oxide and dexamethasone 3 hours after the intervention (P=0.0001). There    was    not    a    significant    difference    in    the    duration    of    labor,    number    of    uterine    contractions    and    infant    complications. Analysis of the maternal vital signs between the two groups showed that none of investigated vital signs    was    significantly    different    between    the    two    groups    except    SBP.    Significant    difference    was    observed    among    the groups regarding Apgar scores in 1st and 5th minutes. Analysis of the pooled risk differences showed that none    of    the    side    effects    investigated    was    significantly    different    between    two    groups    except    nausea    and    vomiting    which        was    significantly    higher    in    nitrous    oxide    users. conclusion:    Use    of    nitrous    oxide    and    dexamethasone    has    more    beneficial    effects    for    many    parturient    women.   
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Type of Study: Applicable | Subject: Gynecologic anesthesia
Received: 2017.07.24 | Accepted: 2018.01.12 | Published: 2018.02.21

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