Volume 1, Issue 3 (23 2010)                   JAP 2010, 1(3): 53-62 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Talebi H, Yazdi B, Alizadeh S, Moshiry E, Nourozi A. Effects of adding two Doses of Midazolam to Lidocaine for Spinal Anesthesia on Post-operative Pain Severity in Patients undergoing Inguinal Herniorrhaphy. JAP. 2010; 1 (3) :53-62
URL: http://jap.iums.ac.ir/article-1-102-en.html
Abstract:   (5139 Views)

Background and aims
The efficacy of adding midazolam to intrathecal bupivacaine has been widely documented. The aim of this study was to assess the effects of combination of intrathecal midazolam and lidocaine on postoperative pain.
In a randomized controlled trial that was performed in 2007 in a teaching hospital of Arak University of Medical Sciences, forty five male patients who were candidates for elective inguinal herniorrhaphy entered and randomly divided into three groups of Control (lidocaine 5% plus Normal saline), M0.5 (lidocaine 5% and midazolam 0.5mg) and M1 (lidocaine 5% and midazolam 1 mg) according to intrathecal solution injected for spinal anesthesia. Mean arterial blood pressure, heart rate, post-operative pain, narcotic requirements, and complications (nausea, vomiting, pruritis, headache, hypotension and bradycardia) were recorded.
The severity of post-operative pain was lowest in M1 group in all postoperative measurements except at 2 hours after operation.There was significant difference in vomiting between three groups which had the highest frequency in M0.5 group. No severe hypotension was seen though, bradycardia occurred in one patient in M0.5 group which needed treatment.
Our findings suggest that administration of intrathecal midazolam (especially 1mg) together with lidocaine is effective in reducing post-operative pain in patients undergoing open inguinal herniorrhaphy and is not associated with adverse effect.

Full-Text [PDF 997 kb]   (974 Downloads)    
Type of Study: Original | Subject: General
Accepted: 2018.12.10 | Published: 2013.06.10

Add your comments about this article : Your username or Email:

© 2019 All Rights Reserved | Anesthesiology and Pain

Designed & Developed by : Yektaweb