fa مقایسه عوارض راه هوایی به دنبال دو روش اکستوباسیون عمیق و بیدار در کودکان تحت بیهوشی عمومی: یک مطالعه مروری سیستماتیک و متاآنالیز بیهوشی اطفال Pediatrics Anesthesia مروری Review <span style="font-size:11pt"><span style="line-height:150%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">مقدمه:</span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:"> با توجه به اینکه عوارض اکستوباسیون در اطفال بسیار بیشتر و خطرناک تر از بزرگسالان می باشد و داده های جامع و کافی که بتوان بر اساس مطالعات انجام شده به آن استناد نمود، در دست نیست مطالعه حاضر با هدف&nbsp; </span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">مقایسه عوارض راه هوایی به دنبال دو روش اکستوباسیون عمیق و بیدار در کودکان تحت بیهوشی عمومی انجام شد.</span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:150%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">روش کار: این مطالعه مروری سیتماتیک و متاآنالیز که بر اساس بیانیه </span></span></span><span dir="LTR" style="font-size:14.0pt"><span style="line-height:150%">PRISMA</span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:"> در طی سال 1401 انجام شد با جستجوی کلیدواژه های </span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">اکستوباسیون، عمیق، بیدار، بیهوشی، اطفال و عوارض </span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">در پایگاه های داده ای</span></span></span> <span dir="LTR" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">&nbsp;MEDLINE</span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">، </span></span></span><span dir="LTR" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">EMBASE</span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">، </span></span></span><span dir="LTR" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">KoreaMed</span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">، ثبت مرکزی کارآزمایی‌های کنترل‌شده کاکرین،</span></span></span> <span dir="LTR" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">CINAH</span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">،</span></span></span><span dir="LTR" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Scopus </span></span></span><span style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">&nbsp;و</span></span></span><span dir="LTR" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> Web of Science </span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">برای جستجوی مقالات انگلیسی و </span></span></span><span dir="LTR" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">SID</span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:"> و </span></span></span><span dir="LTR" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Magiran</span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:"> برای جستجوی مقالات فارسی انجام شد و نتایج کلی گزارش شدند.</span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span style="font-family:"B Nazanin""></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:150%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">نتایج: </span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">11 کارآزمایی تصادفی شده با 1245 شرکت کننده در این مطالعه ارزیابی شدند، </span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">خطر عوارض کلی راه هوایی در گروه اکستوباسیون عمیق کمتر از گروه اکستوباسیون بیدار بود (56/0=</span></span></span><span dir="LTR" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">OR</span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">- 96/0-33/0:</span></span></span> <span dir="LTR" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">CI95%</span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">-04/0=</span></span></span><span dir="LTR" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">P</span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">)؛ همچنین سطح ناهمگنی مقالات در حد متوسطی قرار داشت( 75%=</span></span></span><span dir="LTR" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">I²</span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:"> ).</span></span></span><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span style="font-family:"B Nazanin""></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:150%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><span lang="FA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" nazanin="" style="font-family:">نتیجه گیری: اکتوباسیون عمیق منجر به بروز کمتر عوارض راه هوایی در کودکان تحت بیهوشی عمومی می شود.</span></span></span></span></span></span></span></span><br> &nbsp; <span style="font-size:11pt"><span style="line-height:150%"><span calibri="" style="font-family:"><b><span lang="EN" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Introduction: </span></span></span></b><span lang="EN" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Considering that the complications of extubation in children are much more and more dangerous than in adults and there is no comprehensive and sufficient data that can be cited based on the studies conducted, the present study aims to compare airway complications Two methods of deep and awake extubation were performed in children under general anesthesia. </span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:150%"><span calibri="" style="font-family:"><b><span lang="EN" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Methods:</span></span></span></b><span lang="EN" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> This systematic review and meta-analysis was conducted based on the PRISMA statement during 1401 by searching the keywords extubation, deep, awake, anesthesia, pediatrics and complications in the databases MEDLINE, EMBASE, KoreaMed, Central Registry of Controlled Trials. Cochrane, CINAH, Scopus and Web of Science were searched for English articles and SID and Magiran were searched for Farsi articles and the overall results were reported.</span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:150%"><span calibri="" style="font-family:"><b><span lang="EN" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Results:</span></span></span></b><span lang="EN" style="font-size:14.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> 11 randomized trials with 1245 participants were evaluated in this study, the risk of overall airway complications in the deep extubation group was lower than the awake extubation group (OR=0.56: 0.96-0.33: CI95%-04 /0=P); Also, the level of heterogeneity of the articles was moderate (I2=75%). Conclusion: Deep extubation leads to less incidence of airway complications in children under general anesthesia.</span></span></span></span></span></span><br> &nbsp; عوارض تنفسی, اکستوباسیون, عمیق, سبک, بیهوشی respiratory complications, extubation, deep, light, anesthesia 29 39 http://jap.iums.ac.ir/browse.php?a_code=A-10-421-4&slc_lang=fa&sid=1 sanaz yasrebinia ساناز یثربی نیا Bikaran_mmm@yahoo.com 100319475328460018695 100319475328460018695 No Pediatrice Doctor, Neonatologist, Tabriz University of Medical Sciences, Tabriz, Iran فوق تخصص نوزادان، گروه کودکان، دانشکده پزشکی، دانشگاه علوم پزشکی تبریز، تبریز، ایران Daryoush Sheikhzadeh داریوش شیخ زاده mkhanbabayi@yahoo.com 100319475328460018696 100319475328460018696 Yes Assistant Professor of Anesthesiology, Department of Anesthesiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran استادیار بیهوشی، گروه بیهوشی، دانشکده پزشکی، دانشگاه علوم پزشکی تبریز، تبریز، ایران