Aims and background: Post operative nausea and vomiting is one of the most common complications after surgery. The newest drug for induction and maintenance of anesthesia is propofol. Its consumption due to the rapid onset, short duration of action, Anti-nausea and vomiting property and comfortable feeling after surgery is on the rise. Materials and Methods: In this clinical trial, 90 patients undergoing general surgery were randomly divided into three groups. In the first group induction-dose was 1/5mg/kg propofol, in the second group, induction-dose was 2 mg/kg propofol and in the third group, 2/5mg/kg propofol was used. Based on self-reporting scale and frequency of vomiting, the evaluation condidering the severity and incidence of nausea and vomiting was done in three stages: Exactly after the surgery, and 2 and 6 hours afterwards. Data was analyzed by Spss software. Findings: The results showed that considering age, gender, duration of NPO time, and operation time, no significant difference was found among the three groups. Based on one-way analysis of variance there was no significant difference between groups in severity and incidence of nausea and vomiting. conclusion: Propofol has positive effect incontrolling nausea and vomiting after surgery in different doses. Therefore, administration of Propofol (with divided doses and without the need for pumps) is simple and cheap.

Keywords: propofol, nausea, vomiting

Full-Text [PDF 528 kb]   (28785 Downloads)