TY - JOUR T1 - Comparison effect of intravenous and epidural fentanyl on analgesia and consciousness level in patients with chest and abdominal trauma in intensive care unit TT - مقایسه تزریق وریدی و اپیدورال فنتانیل روی میزان بی دردی و سطح هوشیاری در بیماران دچار تروما به قفسه سینه و شکم در بخش مراقبت های ویژه JF - jap JO - jap VL - 2 IS - 2 UR - http://jap.iums.ac.ir/article-1-72-en.html Y1 - 2011 SP - 24 EP - 33 KW - Epidural KW - fentanyl KW - pain KW - ICU N2 - Background &aim: Several reasons cause to pain in ICU patients. The pain brings some side effects in the patients so that different methods have been introduced for pain reduction. The aim of this study was comparison the effect of epidural fentanyl injection with intravenous fentanyl injection for analgesia and the effect of these two methods on ICU patients' continuousness level.Material and methods: This investigation was a single-blind clinical trial in ICU patients of Shahid Bahonar Hospital in Kerman. These patients suffered from abdominal and chest trauma that were mechanically ventilated. Sixty patients were assessed in two groups. Patients in Group A received intravenous fentanyl for first 24 hrs, and then get epidural fentanyl from epidural catheter. Patients in B group were injected by epidural fentanyl in first 24 hrs, and then by intravenous fentanyl in second 24 hrs. Levels of fentanyl were 1.5 mcg.kg-1 intravenous injection and 8 mcg.kg-1 for epidural injection that were regulated with injection pump. Glascow Coma Scale and Visual Analogue Pain Score were assessed in 0, 2, 6, 24, 50, 54 and 72 hours.Results: In both groups, pain score in 2 hours was significantly lower in intravenous injection than epidural way but after 6 hours, epidural way cause to relieve pain than intravenous way (P M3 ER -