TY - JOUR JF - jap JO - JAP VL - 5 IS - 2 PY - 2014 Y1 - 2014/7/01 TI - The effect of adding epinephrine to 5% lidocaine in spinal anesthesia for cesarean section in patients admitted to Mostafa Khomeini hospital in Ilam TT - تأثیر افزوده شدن اپی نفرین به لیدوکایین 5% در بی حسی نخاعی بیماران سزارینی مراجعه کننده به بیمارستان مصطفی خمینی (ره) ایلام N2 -  Aims and Background : One of the most common surgeries in women is cesarean section. Hence, it is important to choose an anesthetic technique which is safe, appropriate and affordable for mom and baby. Spinal anesthesia is one of such techniques for which drugs with the least possible damage and most efficacy should be chosen. Among the additives to local anesthetics, "epinephrine" is an appropriate choice. Epinephrine is commonly used together with local anesthetic to induce tense block and it seems that adding epinephrine to lidocaine would improve sensory block during spinal anesthesia.  Materials and Methods: This study is a randomized double blind clinical trial. 60 female patients were referred to the operating room of Mostafa Khomeini hospital in Ilam. The patients were divided into two groups receiving lidocaine alone and lidocaine plus epinephrine. The first group received 60mg lidocaine 5% and the second group received 60mg of lidocaine 5% and 0.2 mg epinephrine. Afterward, variables such as systolic blood pressure, diastolic blood pressure, heart rate, respiratory rate, and arterial oxygen saturation by pulse oximetry, level of sensory, motor and sympathetic block, and Apgar score of neonate at 1 and 5 minutes plus possible complications of anesthetic drugs were recorded. Finally the findings were analyzed by multivariate statistical methods.  Findings: We measured different kinds of variables and the results are as follows. Average Pulse Rate after 5 minutes in the first and second groups were, 101/8 ± 31/51 and 107/4 ± 25/04, respectively. This was statistically significant among the groups. A higher level block was more common (with exception in one dermatome) in group one (lidocaine alone) which was confirmed to be statistically different (P SP - 19 EP - 31 AU - Hemmati, Karim AU - Sayadizadeh, Tayebeh AU - Delpisheh, Ali AU - Ahmadian Mazhyn, Zahra AD - Ilam University of medical sciences KW - cesarean section KW - epinephrine KW - lidocaine UR - http://jap.iums.ac.ir/article-1-5128-en.html ER -