Volume 4, Number 3 (spring 2015)                   JAP 2015, 4(3): 54-61 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Hassan V, Farhadi M, Zaman B, Aali N, Safaeian R, Sayarifard A. Comparison between intravenous acetaminophen and remifentanil on the airway response to tracheal tube in endoscopic sinus surgery, during and at the end of anesthesia. JAP. 2015; 4 (3) :54-61
URL: http://jap.iums.ac.ir/article-1-5119-en.html

1- Professor of Anesthesiology Hazrat Rasool Akram Hospital, Iran University of Medical Sciences
2- Professor of Otolaryngology-Head and Neck Surgery ENT and Head Neck Surgery Research Center, Iran University of Medical Sciences
3- Assistant Professor of Anesthesiology Iran University of Medical Sciences
4- Resident of Anesthesiology Iran University of Medical Sciences , nasim_a1355@yahoo.com
5- Assistant Professor of Community Medicine Tehran University of Medical Sciences
Abstract:   (10624 Views)

Aims and Background: Airway hyperactivity is one of the most important complications of tracheal extubation. This study was designed to compare the efficacy of intravenous acetaminophen as an alternative to remifentanil on airway response to tracheal tubes during and at the end of anesthesia in functional endoscopic sinus surgery.

Methods and materials: This study was conducted as a double blind clinical trial on 70 patients 20 to 60 years old, candidate for endoscopic sinus surgery, in Rasoul-Akram hospital. They were randomly allocated into two groups: the Paracetamol (n=35) and the remifentanil (n=35) groups. Remifentanil infusion with a dose of 0 /1μg/kg/min was administered for both groups during anesthesia . Since the beginning of inserting the nose tampon until extubation, remifentanil infusion (0/1 μg/kg/min ) was continued in group I, and in group II in the last 20 minutes of surgery , remifentanil infusion was discontinued and intravenous injection of acetaminophen was begun . Incidece of Cough, Arterial blood pressure, and heart rate were recorded.

Findings : There was no significant difference in the incidence rate of cough during extubation between the two groups (P=0.7). M ean arterial pressure (MAP) v ariation, was significantly lower in the remifentanil group (P<0.001). Variations in heart rate were similar in both groups ( P=0.74).

Conclusions: Using intravenous acetaminophen has the same effect as remifentanil in controling airway reflexes after endoscopic sinus surgery as well as reducing symptoms such as restlessness and changes in heart rate.

Full-Text [PDF 356 kb]   (618 Downloads)    
Type of Study: Original | Subject: Acute pain managment
Received: 2014.06.11 | Accepted: 2014.06.11 | Published: 2014.06.11

Add your comments about this article : Your username or email:
Write the security code in the box

Send email to the article author


© 2015 All Rights Reserved | Anesthesiology and Pain

Designed & Developed by : Yektaweb